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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDX1
All Species:
23.64
Human Site:
S273
Identified Species:
47.27
UniProt:
P52945
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52945
NP_000200.1
283
30771
S273
S
A
S
P
Q
P
S
S
V
A
P
R
R
P
Q
Chimpanzee
Pan troglodytes
A2T756
283
30712
S273
S
A
S
P
Q
P
S
S
V
A
P
R
R
P
Q
Rhesus Macaque
Macaca mulatta
XP_001096758
281
30575
S271
S
A
S
P
Q
P
S
S
V
A
P
R
R
P
Q
Dog
Lupus familis
XP_543155
532
56855
S522
S
A
S
P
Q
P
S
S
V
A
P
V
R
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P52946
284
30981
S274
S
V
S
P
Q
P
S
S
I
A
P
L
R
P
Q
Rat
Rattus norvegicus
P52947
283
30812
S273
S
A
S
P
Q
P
S
S
I
A
P
L
R
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519548
259
28495
P249
R
D
P
G
V
P
A
P
G
M
T
P
R
P
Q
Chicken
Gallus gallus
XP_001234636
231
26345
V217
A
D
P
E
Q
D
C
V
V
S
S
G
K
L
Q
Frog
Xenopus laevis
P14837
271
31388
I262
Q
P
N
Q
V
P
S
I
G
S
L
R
Q
A
E
Zebra Danio
Brachydanio rerio
O42370
396
43083
C355
S
A
S
V
D
Y
S
C
A
A
Q
I
P
G
N
Tiger Blowfish
Takifugu rubipres
Q1KKS7
408
44369
S366
S
S
T
S
V
D
Y
S
C
A
A
Q
I
P
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999815
390
43430
Q379
S
S
N
I
R
P
S
Q
V
K
P
Q
I
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.2
49.6
N.A.
87.6
88.6
N.A.
64.3
63.2
57.9
26.7
26.9
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
99.2
98.5
50
N.A.
89.4
90.1
N.A.
71
70.6
66.7
36.6
36.7
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
26.6
20
20
33.3
26.6
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
33.3
40
46.6
33.3
46.6
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
50
0
0
0
0
9
0
9
67
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
9
17
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
17
0
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
17
0
0
9
17
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
9
17
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
17
50
0
75
0
9
0
0
59
9
9
67
0
% P
% Gln:
9
0
0
9
59
0
0
9
0
0
9
17
9
0
67
% Q
% Arg:
9
0
0
0
9
0
0
0
0
0
0
34
59
0
0
% R
% Ser:
75
17
59
9
0
0
75
59
0
17
9
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
9
0
9
25
0
0
9
50
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _